Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Auteur(s) : McCarthy, J. R.
Titre(s) : Enzyme technologies [Texte électronique] : pluripotent players in discovering therapeutic agents / J.R. McCarthy, Hsiu-Chiung Yang, Wu-Kuang Yeh
Publication : Hoboken, New Jersey : Wiley-Interscience, [2014]
Description matérielle : 1 online resource
Collection : Chemical Biology of Enzymes for Biotechnology and Pharmaceutical Applications ; Volume
II
Note(s) : Includes bibliographical references and index. - Print version record and CIP data provided by publisher.
"This book highlights how, what, and where enzymes have become critical in pharmaceutical
and biotechnology research. It provides in-depth reviews of recent developments in
select topics on biosynthesis, biocatalysis, and chemical biology of enzymes. Broad
coverage of enzymatic assays includes emerging assay technologies for key enzyme classes
in pharmaceutical research. In addition to new developments in proteomics, this book
includes two emerging technologies in Life Sciences: metabolomics (including glycomics
and lipidomics) and preclinomics. This volume reviews important progress on the chemical
biology of enzymes in the post-genomic era"
Autre(s) auteur(s) : Yang, Hsiu-Chiung. Fonction indéterminée
Yeh, Wu-Kuang (1942-....). Fonction indéterminée
Sujet(s) : Antienzymes
Enzymes -- Pharmacocinétique
Sciences -- Biotechnologie
Indice(s) Dewey :
615.3 (23e éd.) = Médicaments d'origine organique
Identifiants, prix et caractéristiques : ISBN 9781118739907
Identifiant de la notice : ark:/12148/cb44654952s
Notice n° :
FRBNF44654952
(notice reprise d'un réservoir extérieur)
Table des matières : Machine generated contents note: pt. A ENZYMES ; ESSENTIAL WORKHORSES IN PHARMACEUTICAL
RESEARCH ; 1. Assay Technologies for Proteases / Rathnam Chaguturu ; 2. Discovery
and Development of Isozyme-Selective Inhibitors Involved in Lipid Metabolism / Hiroshi
Tomoda ; 3. Covalent Enzyme Inhibition in Drug Discovery and Development / Shujaath
Mehdi ; 4. Preclinomics: Enzyme Assays and Rodent Models for Metabolic diseases /
Richard G. Peterson ; pt. B ENZYMES ; INDISPENSABLE TOOLS FOR IMPROVING DRUGGABILITY
; 5. Enzymes and Targeted Activation of Prodrugs / Longqin Hu ; 6. Evolution of
an Orally Active Prodrug of Gemcitabine / James R. McCarthy ; 7. Enzymatically Activated
Phosphate and Phosphonate Prodrugs / Charles E. McKenna ; pt. C ENZYMES ; POWERFUL
WEAPONS FOR CORRECTING NATURE'S ERRORS ; 8. Treatment Options for Mucopolysaccharidosis
Type II (Hunter's Syndrome) / Michael Beck ; 9. Enzyme Replacement Therapy for Fabry
Disease / Ozlem Goker-Alpan ; 10. Methods and Pri