Type(s) de contenu et mode(s) de consultation : Texte noté : électronique

Auteur(s) : Burcham, Philip C.  Voir les notices liées en tant qu'auteur

Titre(s) : An introduction to toxicology [Texte électronique] / Philip C. Burcham

Publication : London : Springer, cop. 2014

Description matérielle : 1 ressource dématérialisée

Note(s) : Includes bibliographical references and index
"This book provides a readable introduction to modern toxicology with a particular focus on the mechanisms underlying the induction of toxicity by foreign substances. Since bioactivation is central to many toxic syndromes, special interest is devoted to chemicals that undergo conversion to toxic metabolites that induce toxic effects as diverse as cancer, birth defects and organ injury. The molecular consequences accompanying damage to cellular DNA and proteins is explored together with the relevance of toxicological paradigms to human diseases caused by alcohol and tobacco. The discipline of toxicology has developed rapidly since the thalidomide disaster in the 1960?s as scientists worldwide seek to understand the adverse health effects of human medicines, environmental pollutants, consumer chemicals and industrial reagents. An Introduction to Toxicology is intended to supplement the recommended reading list of undergraduate and graduate programs in toxicology and pharmacology as an enjoyable, accessible primer with illustrations that "unpack" the concepts being discussed in the text"--Back cover

Sujet(s) : Toxicologie  Voir les notices liées en tant que sujet

Indice(s) Dewey :  615.9 (23e éd.) = Toxicologie (médecine)  Voir les notices liées en tant que sujet

Identifiants, prix et caractéristiques : ISBN 9781447155539

Identifiant de la notice  : ark:/12148/cb44663638c

Notice n° :  FRBNF44663638 (notice reprise d'un réservoir extérieur)

Table des matières : The emergence of modern toxicology ; Core concepts in toxicology ; Toxicokinetics : the fate of chemicals within the body ; Toxicodynamics : how chemicals induce toxicity ; Fightback : adaptive responses to toxicant exposure ; Target organ toxicity: liver and kidney ; Chemical toxicity to the unborn ; Chemicals and cancer ; Everyday toxicology I : alcohol ; Everyday toxicology II: tobacco.