Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Titre(s) : Toxoplasma gondii [Texte électronique] : the model apicomplexan : perspectives and methods / edited by Louis M. Weiss and Kami Kim
Édition : 1st ed.
Publication : Amsterdam ; Boston : Elsevier/Academic Press, 2007
Description matérielle : 1 ressource dématérialisée
Note(s) : Includes bibliographical references and index
Toxoplasmosis is caused by a one-celled protozoan parasite known as Toxoplasma gondii.
In the United States, it is estimated that approximately 30% of cats, the primary
carriers, have been infected by T. gondii. Most humans contract toxoplasmosis by eating
cyst-contaminated raw or undercooked meat, vegetables, or milk products or when they
come into contact with the T. gondii eggs from cat feaces while cleaning a cat's litterbox,
gardening, or playing in a sandbox. Approx 1 in 4 (more than 60 million) people in
the USA are infected with the parasite, and in the UK between 0.5 and 1% of individuals
become infected each year. By the age of 50, 40% of people test positive for the parasite.
The predilection of this parasite is for the central nervous system (CNS) causing
behavioral and personality alterations as well as fatal necrotizing encephalitis,
and is especially dangerous for HIV infected patients. Though there have been tremendous
strides in our understanding of the biology of Toxoplasma gondii in the last decade,
there has been no systemic review of all of the information that has accumulated.
Toxoplasma gondii provides the first comprehensive summary of literature on this organism
by leading experts in the field who were responsible for organising the 7th International
Congress on Toxoplasmosis in May 2003. It offeres systematic reviews of the biology
of this pathogen as well as descriptions of the methods and resources used. Within
the next year the T. gondii genome will be completed making this an indispensable
research resource for biologists, physicians, parasitologists, and for all those contemplating
experiments using T. gondii. * Serves as a model for understanding invasion of host
cells by parasites, immune response, motility, differentiation, phylogenetics, evolution
and organelle acquisition * Discusses the protocols related to genetic manipulation,
cell biology and animal models while also providing reference material on available
resources for working with this organism
Autre(s) auteur(s) : Weiss, Louis M.. Fonction indéterminée
Kim, Kami. Fonction indéterminée
Sujet(s) : Toxoplasma gondii
Toxoplasmose
Indice(s) Dewey :
615.372 (23e éd.) = Vaccins (pharmacologie)
Identifiants, prix et caractéristiques : ISBN 9780123695420
Identifiant de la notice : ark:/12148/cb44633430f
Notice n° :
FRBNF44633430
(notice reprise d'un réservoir extérieur)
Table des matières : The history and life cycle of Toxoplasma gondii / J.P. Dubey ; The ultrastrcuture
of Toxoplasm gondii / D.J.P. Ferguson and J.F. Dubremetz ; Population structure and
epidemiology of Toxoplasma gondii / M.L. Dardé, D. Ajzenberg, and J. Smith ; Clinical
disease and diagnostics / E. Petersen and O. Liesenfeld ; Ocular disease due to Toxoplasma
gondii / P. Latkany ; Toxoplasmosis in wild and domestic animals / D.S. Lindsay and
J.P. Dubey ; Toxoplasma animal models and therapeutics / U. Reichard and U. Gross
; Biochemistry and metabolism of Toxoplasma gondii / T. Asai and S. Tomavo ; the
apicoplast and mitochondrion of Toxoplasma gondii / J.E. Feagin and M. Parsons ;
Calcium storage and homeostasis in Toxoplasma gondii / S.N.J. Moreno [and others]
; Toxoplasma secretory proteins and their roles in cell invasion and intracellular
survival / M. Lebrun, V.B. Carruthers, and M.-E. Cesbron-Delauw ; Alterations in
host-cell biology due to Toxoplasma gondii / J.D. Dunn [and others].
Bradyzoite development / L.M. Weiss and K. Kim ; Development and applications of classical
genetics in Toxoplasma gondii / J.W. Ajioka and L.D. Sibley ; Genetic manipulation
of Toxoplasma gondii / B. Striepen and D. Soldati ; Gene regulation / M.W. White
[and others] ; The surface protein repertoire and expanded gene families of Toxoplasma
gondii and other apicomplexa / T.J. Templeton ; Comparative aspects of nucleotide
and amino-acid metabolism in Toxoplasma gondii and other apicomplexa / K. Chaudhary,
B.A. Fox, and D.J. Bzik ; Toxoplasma as a model system for apicomplexan drug discovery
/ R.G.K. Donald ; Proteomics of Toxoplasma gondii / J.M. Wastling ; Cerebro toxoplasmosis:
pathogenesis and host resistance / Y. Suzuki [and others] ; Innate immunity in Toxoplasma
gondii infection / D. Buzoni-Gatel and L.H. Kasper ; Adaptive immunity and genetics
of the host immune response / C.W. Roberts [and others] ; Vaccination against toxoplasmosis:
current status and future prospe
