Type(s) de contenu et mode(s) de consultation : Texte noté : électronique

Titre(s) : Nuclear receptors [Texte électronique] : current concepts and future challenges / edited by Chris M. Bunce, Moray J. Campbell

Publication : Dordrecht [Netherlands] ; New York : Springer, cop. 2010

Description matérielle : 1 ressource dématérialisée

Collection : Proteins and cell regulation ; v. 8

Note(s) : Includes bibliographical references and index
'In 1980 a case of myxedema was treated in Lisbon by the implantation of a sheep thyroid gland with the immediate improvement in the patients condition. A few years later, medications for the then ill-explained condition of the menopause included tablets made from cow ovaries. In the first quarter of the 20th century the identification vitamin D3 and its sunlight driven production in skin paved the way to the elimination of rickets as a major medical problem. Twenty years or so later Sir Vincent Wigglesworth established the endocrine basis of developmental moulting in insects, arguably the most commonly performed animal behaviour on Planet Earth. A paradigm that would unify these disparate observations arose between in 1985 and 1987 beginning with the identification of the glucocorticoid receptor and the nuclear receptor super-family. What follows is a timely and positive manifestation of the capacity, productivity and value of international human scientific endeavour. Based on intrigue, lively competition and cooperation a global effort has rapidly fostered a school of biology with widespread ramifications for the understanding of metazoan animals, the human condition and the state of the planet. This book is the first this century to try and capture the spirit of this endeavour, to depict where the field is now and to identify some of the challenges and opportunities for the future.' -- From book cover

Autre(s) auteur(s) : Bunce, Chris M.. Fonction indéterminée  Voir les notices liées en tant qu'auteur
Campbell, Moray J.. Fonction indéterminée  Voir les notices liées en tant qu'auteur

Sujet(s) : Récepteurs nucléaires (biochimie)  Voir les notices liées en tant que sujet

Indice(s) Dewey :  571.6 (23e éd.) = Biologie cellulaire  Voir les notices liées en tant que sujet

Identifiants, prix et caractéristiques : ISBN 9789048133031

Identifiant de la notice  : ark:/12148/cb447199003

Notice n° :  FRBNF44719900 (notice reprise d'un réservoir extérieur)

Table des matières : Nuclear receptors an introductory overview / C.M. Bunce and M.J. Campbell ; What does evolution teach us about nuclear receptors? / G. Markov, F. Bonneton and V. Laudet ; Functions of nuclear receptors in insect development / D. Martín ; The glucocorticoid receptor / R.H. Oakley and J.A. Cidlowski ; Estrogen receptors: Their actions and functional roles in health and disease / S. Nilsson and J.-Å. Gustafsson ; Androgen receptor / J.T. Dalton and W. Gao ; Thyroid hormone receptors / B. Vennström, H. Liu and D. Forrest ; The vitamin D receptor (NR1I1) / O. Maguire and M.J. Campbell ; Retinoic acid receptors / A. Cras, F. Guidez and C. Chomienne ; PPARs: Important regulators in metabolism and inflammation / L.M. Sanderson and S. Kersten ; Xenobiotic receptors CAR and PXR / C. Klaassen and H. Lu ; Fxr / Y. Wang [and others] ; Physiological functions of TR2 and TR4 orphan nuclear receptor / S. Liu [and others] ; Nuclear receptors and ATP dependent chromatin remodel