Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Titre(s) : Molecular analysis of B lymphocyte development and activation [Texte électronique] / H. Singh and R. Grosschedl (ed.)
Publication : Berlin ; New York : Springer, cop. 2005
Description matérielle : 1 online resource (viii, 255 pages)
Collection : Current topics in microbiology and immunology ; 290
Note(s) : Includes bibliographical references and index
The B lymphocyte lineage represents an important paradigm for exploring the molecular
mechanisms underlying cell fate specification, differentiation and cellular activation.
In the past five years, major advances have been achieved in our understanding of
the transcriptional control of early B cell development and terminal plasma cell differentiation.
In addition new insights became available for the processes of B cell activation,
class switch recombination and somatic hypermutation. Many of the new findings and
their implications for a molecular understanding of B cell biology in particular and
cell differentiation in general are covered in this volume
Autre(s) auteur(s) : Singh, Harinder (1957-....). Fonction indéterminée
Grosschedl, Rudolf. Fonction indéterminée
Sujet(s) : Lymphocytes -- Activation
Lymphocytes B
Lymphocytes
Sciences de la vie
Indice(s) Dewey :
616.079 (23e éd.) = Immunité (médecine)
Identifiants, prix et caractéristiques : ISBN 9783540263630
Identifiant de la notice : ark:/12148/cb44684288g
Notice n° :
FRBNF44684288
(notice reprise d'un réservoir extérieur)
Table des matières : Gene regulatory networks orchestrating B cell fate specification, commitment, and
differentiation / K.L. Medina, H. Singh ; Helix-loop-helix proteins in lymphocyte
lineage determination / B.L. Kee ; Ikaros-family proteins : in search of molecular
functions during lymphocyte development / B.S. Cobb, S.T. Smale ; Biochemistry of
V(D)J recombination / D.G. Schatz, E. Spanopoulou ; The pre-B cell receptor in B
cell development : recent advances, persistent questions and conserved mechanisms
/ M.R. Clark [and others] ; Transcriptional control of B cell activation / L.M. Corcoran
; Expression of MHC II genes / G. Drozina [and others] ; Class switch recombination
: an emerging mechanism / A.L. Kenter ; Blimp-1 ; Immunoglobulin secretion and the
switch to plasma cells / R. Schiammas, M.M. Davis ; Wnt signaling in lymphopoiesis
/ A. Timm, R. Grosschedl.