Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Titre(s) : Translational stroke research [Texte électronique] : from target selection to clinical trials / Paul A. Lapchak, John H. Zhang, eds
Publication : New York : Springer, 2012
Description matérielle : 1 ressource dématérialisée
Collection : Springer series in translational stroke research
Note(s) : Includes bibliographical references and index
Autre(s) auteur(s) : Lapchak, Paul A.. Fonction indéterminée
Zhang, John H.. Fonction indéterminée
Sujet(s) : Maladies cérébrovasculaires -- Recherche
Identifiants, prix et caractéristiques : ISBN 9781441995308
Identifiant de la notice : ark:/12148/cb44662198m
Notice n° :
FRBNF44662198
(notice reprise d'un réservoir extérieur)
Table des matières : pt. 1 ; Theoretical overview -- ; Vascular targets for ischemic stroke treatment /Sara
Morales Palomares and Marilyn J. Cipolla ; Identifying vascular targets to treat hemorrhagic
stroke /Paul A. Lapchak ; Experimental platforms for assessing white matter pathophysiology
in stroke /Ken Arai, Loc-Duyen D. Pham and Eng H. Lo ; Neuroprotection in stroke /Aarti
Sarwal, Muhammad Shazam Hussain and Ashfaq Shuaib
pt. 2 ; Mechanisms & Targets -- ; Protein aggregation and multiple organelle damage
after brain ischemia /Chunli H. Liu, Fan Zhang, Tibor Krisrian, Brian Polster and
Gary M. Fiskum, et al. ; Antioxidants and stroke: success and pitfalls /Fernanda M.F.
Roleira, Elisiário J. Tavares-da-Silva, Jorge Garrido and Fernanda Borges ; Caspase-independent
stroke targets /Ruoyang Shi, Jiequn Weng, Paul Szelemej and Jiming Kong ; Hypoxia-inducible
factor: a new hope to counteract stroke /Chunhua Chen and Changman Zhou ; Thrombin
in ischemic stroke targeting /Bo Chen ; Toll-like receptor agonists as antecedent
therapy for ischemic brain injury: advancing preclinical studies to the nonhuman primate
/Frances Rena Bahjat, Keri B. Vartanian, G. Alexander West and Mary P. Stenzel-Poore
; Angiogenesis and arteriogenesis as stroke targets /Jieli Chen and Michael Chopp
; Hematopoietic growth factor family for stroke drug development /Ihsan Solaroglu
and Murat Digicaylioglu ; Soluble epoxide hydrolase as a stroke
pt. 3 ; Translational models -- ; overcoming barriers to translation from experimental
stroke models /Ludmila Belayev ; Animal models of stroke for preclinical drug development:
a comparative study of flavonols for cytoprotection /Carli L. Roulston, Sarah McCann,
Robert M. Weston and Bevyn Jarrott ; Clinical relevance in a translational rodent
model of acute ischemic stroke: incorporating the biological variability of spontaneous
recanalization /Kama Guluma ; A clinically relevant rabbit embolic stroke model for
acute ischemic stroke therapy development: mechanisms and targets /Paul A. Lapchak
; Animal models of intracranial aneurysms /Elena I. Liang, Hiroshi Makino, Yoshiteru
Tada, Kosuke Wada and Tomoki Hashimoto ; Animal models of sah and their translation
to clinical sah /Tommaso Zoerle and R. Loch Macdonald
pt. 4 ; De-risking of Drug Candidates -- ; ADME (absorption, distribution, metabolism,
excretion): the real meaning-avoiding disaster and maintaining efficacy for preclinical
candidates /Katya Tsaioun and Steven A. Kates ; CeeTox analysis to de-risk drug development:
the three antioxidants (NXY-059, Radicut, and STAZN) /Paul A. Lapchakpt. 5 ; Therapy
Delivery -- ; Site-specific, sustained-release drug delivery for subarachnoid hemorrhage
/R. Loch Macdonald ; Therapeutic potential of intranasal delivery of drugs and cells
for stroke and other neurological diseases /Heyu Chen, Caibin Sheng, Weiliang Xia
and Weihai Ying
pt. 6 ; Therapy Development -- ; High-dose albumin for neuroprotection in acute ischemic
stroke: from basic investigations to multicenter clinical trial /Myron D. Ginsberg
; The translation procedure of low-level laser therapy in acute ischemic stroke: a
nonpharmaceutics noninvasive method /Yair Lampl ; Use of microbubbles in acute stroke
/Marta Rubiera and Carlos A. Molina ; Transcranial high-intensity focused ultrasound
for sonothrombolysis in stroke /Thilo Hölscher, Golnaz Ahadi, Daniel Lotz, Cheryl
Schendel and David Fisher, et al. ; Cellular therapy for ischemic stroke /Todd Deveau,
Shan Ping Yu and Ling Wei
