Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Titre(s) : Telomerases [Texte électronique] : chemistry, biology and clinical applications / edited by Neal F. Lue and Chantal Autexier
Publication : Hoboken : John Wiley & Sons, 2012
Description matérielle : 1 online resource (1 texte électronique (x, [16], 308 p.))
Note(s) : In Wiley online library. - Titre de l'écran-titre (visionné le 31 juillet 2012). - Bibliogr
"This book is a comprehensive and up-to-date review and evaluation of the contemporary
status of telomerase research. Chapters in this volume cover the basic structure,
mechanisms, and diversity of the essential and regulatory subunits of telomerase.
Other topics include telomerase biogenesis, transcriptional and post-translational
regulation, off-telomere functions of telomerase and the role of telomerase in cellular
senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile
genetic elements that shares similarities with telomerase and serves as telomeres
in selected organisms, are also reviewed"--Résumé de l'éditeur
Autre(s) auteur(s) : Lue, Neal F. (1962-....). Fonction indéterminée
Autexier, Chantal (1963-....). Fonction indéterminée
Sujet(s) : Télomérase
Indice(s) Dewey :
572.7 (23e éd.) = Enzymes ; 572.8 (23e éd.) = Génétique biochimique ; 572.86 (23e éd.) = ADN
Identifiants, prix et caractéristiques : ISBN 9781118268667
Identifiant de la notice : ark:/12148/cb44653000t
Notice n° :
FRBNF44653000
(notice reprise d'un réservoir extérieur)
Table des matières : The telomerase complex : an overview / Johanna Mancini and Chantal Autexier ; Telomerase
RNA : structure, function, and molecular mechanisms / Yehudi Tzfati and Julian J.-L.
Chen ; TERT structure, function, and molecular mechanisms / Emmanuel Skordalakes
and Neal F. Lue ; Telomerase biogenesis : RNA Processing, trafficking and protein
Interactions / Tara Beattie and Pascal Chartrand ; Transcriptional regulation of
human telomerase / Antonella Farsetti and Yu-Sheng Cong ; Telomerase regulation and
telomere length homeostasis / Joachim Lingner and David Shore ; Telomere structure
in telomerase regulation / Momchil D. Vodenicharov and Raymund J. Wellinger ; Off-telomere
functions of telomerase / Kenkichi Masutomi and William C. Hahn ; Murine Models of
Dysfunctional Telomeres and Telomerase / Yie Liu and Lea Harrington ; Cellular senescence,
telomerase, and cancer in human cells / Phillip G. Smiraldo ... [et al.] ; Telomerase,
retrotransposons, and evolution / Irina R. Arkhipo