Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Auteur(s) : Steinberg, Daniel (1922-2015)
Titre(s) : The cholesterol wars [Texte électronique] : the skeptics vs. the preponderance of evidence / Daniel Steinberg
Édition : 1st ed.
Publication : San Diego, Calif. : Academic Press, 2007
Description matérielle : 1 ressource dématérialisée
Note(s) : Includes bibliographical references and index
Today, in the era of the statins (cholesterol lowering drugs), there is no longer
any doubt about the value of lowering blood cholesterol levels. This book chronicles
the controversy that swirled around the 'lipid hypothesis' of atherosclerosis for
so many years. In fact, 'the lower the better' is the position of many clinicians.
However, getting to this point has been a long uphill battle marked by heated debate
and sometimes violent disagreement. The history of this controversy is told here for
its own sake and because remembering it may help us avoid similar mistakes in the
future. * Dr. Steinberg and his colleagues have published over 400 papers relating
to lipid and lipoprotein metabolism and atherosclerosis reflecting the prominence
these authors have in the community. * Chronicles the miraculous power of the statins
to prevent heart attacks and save lives, of great interest to the many manufacturers
of these drugs * Discusses new targets for intervention based on a better understanding
of the molecular basis of atherosclerosis
Sujet(s) : Artériosclérose -- Étiologie
Athérosclérose
Statines
Indice(s) Dewey :
616.136 (23e éd.) = Artériosclérose (médecine)
Identifiants, prix et caractéristiques : ISBN 9780123739797
Identifiant de la notice : ark:/12148/cb446337668
Notice n° :
FRBNF44633766
(notice reprise d'un réservoir extérieur)
Table des matières : Thoughts on the nature of medical controversy in general and an overview of the cholesterol
controversy in particular ; Animal models of atherosclerosis ; Early evidence linking
hypercholesterolemia to atherosclerosis and coronary heart disease ; Lipoproteins
and metabolism ; In search of a pathogenesis ; Basic science foundations ; Searching
for drugs that would lower blood cholesterol safely and effectively ; 1984 coronary
primary prevention trial ; Statins ; A look at the future.
