Type(s) de contenu et mode(s) de consultation : Texte noté : électronique

Auteur(s) : Alibardi, Lorenzo  Voir les notices liées en tant qu'auteur

Titre(s) : Morphological and cellular aspects of tail and limb regeneration in lizards [Texte électronique] : a model system with implications for tissue regeneration in mammals / Lorenzo Alibardi

Publication : Heidelberg : Springer, cop. 2010

Description matérielle : 1 ressource dématérialisée

Collection : Advances in anatomy, embryology and cell biology ; 207

Note(s) : Includes bibliographical references and index
"The present review deals with the analysis of the cytological processess occurring during tissue regeneration in the tail and limb of lizards. These reptiles are considered as a model to understand the process of tissue regeneration in all amniotes. The review begins with some evolutive considerations on the origin of tail regeneration in comparison to the failure of limb regeneration, a unique case among amniotes. The formation of the tail in the embryo and the possible accumulation of stem cells in autotomous planes of the tail are discussed. The histological and ultrastructural processess occuring during blastema formation and tail regeneration and during limb cicatrization are presented. The comparison stresses the scarse to absent inflammatory reaction present in the tail vs the massive inflammatory response in the limb leading to scarring. In fact the experimental induction of a strong inflammation in the tail also leads to scarring. The importance of the nervous system in stimulating tail regeneration in lizards is emphasized. The presence of growth factors and extracellular matrix proteins during wound healing of the tail and limb is introduced. The review concludes stressing the importance of the lizard model of tissue regeneration for medical studies and applications."--Publisher's website

Sujet(s) : Lézards -- Cytologie  Voir les notices liées en tant que sujet
Régénération (biologie)  Voir les notices liées en tant que sujet

Identifiants, prix et caractéristiques : ISBN 9783642037337

Identifiant de la notice  : ark:/12148/cb446985514

Notice n° :  FRBNF44698551 (notice reprise d'un réservoir extérieur)

Table des matières : Regeneration in Reptiles and Its Position Among Vertebrates ; Tail Regeneration: Ultrastructural and Cytological Aspects ; Limb Regeneration: Ultrastructural and Cytological Aspects ; Conclusion and Perspectives: Implications for Human Regeneration.