Type(s) de contenu et mode(s) de consultation : Texte noté : électronique

Titre(s) : Biochemistry of collagens, laminins and elastin [Texte électronique] : structure, function and biomarkers / edited by Morten A. Karsdal ; co-editors, Diana J. Leeming... [et al.]

Édition : 2nd ed.

Publication : London : Academic press, an imprint of Elsevier, 2019

Description matérielle : 1 online resource

Note(s) : Notes bibliogr. Index
There are 28 different collagens, with 46 unique chains, which allows for a collagen for each time and place. Some collagens are specialized for basement membrane, whereas others are the central structural component of the interstitial matrix. There are eight collagens among the 20 most abundant proteins in the body, which makes these molecules essential building blocks of tissues. In addition, lessons learned from monogenomic mutations in these proteins result in grave pathologies, exemplifying their importance in development. These molecules, and their post-translationally modified products serve as biomarkers of diseases in a range of pathologies associated with the extracellular matrix. Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers, Second Edition provides researchers and students current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of proteins can result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions that may be viewed as endocrine function, and it highlights how this knowledge can be exploited to modulate fibrotic disease
La pagination de l'édition imprimée correspondante est de : XLIV-389 p.

Autre(s) auteur(s) : Karsdal, Morten A.. Éditeur scientifique  Voir les notices liées en tant qu'auteur

Sujet(s) : Collagène -- Physiologie  Voir les notices liées en tant que sujet
Élastine -- Cytopathologie  Voir les notices liées en tant que sujet
Marqueurs biologiques  Voir les notices liées en tant que sujet

Indice(s) Dewey :  572.67 (23e éd.) = Protéines de structure (biochimie)  Voir les notices liées en tant que sujet

Identifiants, prix et caractéristiques : ISBN 9780128170687. - ISBN 0128170689

Identifiant de la notice  : ark:/12148/cb46841316z

Notice n° :  FRBNF46841316 (notice reprise d'un réservoir extérieur)

Table des matières : Introduction ; Chapter 1. Type I collagen / K. Henriksen and M.A. Karsdal ; Chapter 2. Type II collagen / Y. He, N.S. Gudmann, ... C.S. Thudium ; Chapter 3. Type III collagen / M.J. Nielsen, I.F. Villesen, ... M.A. Karsdal ; Chapter 4. Type IV collagen / J.M.B. Sand, F. Genovese, ... M.A. Karsdal ; Chapter 5. Type V collagen / D.J. Leeming and M.A. Karsdal ; Chapter 6. Type VI collagen / S. Sun, F. Genovese and M.A. Karsdal ; Chapter 7. Type VII collagen / J.H. Mortensen and M.A. Karsdal ; Chapter 8. Type VIII collagen / N.U.B. Hansen, N.S. Gudmann and M.A. Karsdal ; Chapter 9. Type IX collagen / Y. He, S. Sardar and M.A. Karsdal ; Chapter 10. Type X collagen / Y. He, N.S. Gudmann, ... M.A. Karsdal ; Chapter 11. Type XI collagen / Y.Y. Luo, P.M. Szlarski, ... M.A. Karsdal ; Chapter 12. Type XII collagen / J.H. Mortensen, T. Manon-Jensen and M.A. Karsdal ; Chapter 13. Type XIII collagen / A.S. Siebuhr, C.S. Thudium and M.A. Karsdal ; Chapter 14. Type XIV collagen / M. Lindholm, T. Manon-Jensen and M.A. Karsdal ; Chapter 15. Type XV collagen / T. Manon-Jensen, A. Arvanitidis and M.A. Karsdal ; Chapter 16. Type XVI collagen / J.M.B. Sand, C. Jensen and M.A. Karsdal ; Chapter 17. Type XVII collagen / S. Sun and M.A. Karsdal ; Chapter 18. Type XVIII collagen / M. Pehrsson, C.L. Bager and M.A. Karsdal ; Chapter 19. Type XIX collagen / S. Holm Nielsen and M.A. Karsdal ; Chapter 20. Type XX collagen / N. Willumsen, N.I. Nissen and M.A. Karsdal ; Chapter 21. Type XXI collagen / S.N. Kehlet, H. Jessen and M.A. Karsdal ; Chapter 22. Type XXII collagen / S.N. Kehlet, H. Jessen and M.A. Karsdal ; Chapter 23. Type XXIII collagen / S.N. Kehlet, H. Jessen and M.A. Karsdal ; Chapter 24. Type XXIV collagen / S. Holm Nielsen and M.A. Karsdal ; Chapter 25. Type XXV collagen / L.L. Langholm, N.G. Kjeld and M.A. Karsdal ; Chapter 26. Type XXVI collagen / T. Manon-Jensen, N.G. Kjeld and M.A. Karsdal ; Chapter 27. Type XXVII collagen / F. Genovese and M.A. Karsdal ; Chapter 28. Type XXVIII collagen / N. Sparding, A. Arvanitidis and M.A. Karsdal ; Chapter 29. Laminins / D.G.K. Rasmussen and M.A. Karsdal ; Chapter 30. Elastin / J.H. Kristensen, J. Thorlacius-Ussing, ... M.A. Karsdal ; Chapter 31. The collagen chaperones / S.N. Kehlet, A.S. Siebuhr, ... M.A. Karsdal ; Chapter 32. Collagen diseases / S. Sardar, M.A. Karsdal and K. Henriksen ; Chapter 33. The signals of the extracellular matrix / A.L. Reese-Petersen, F. Genovese and M.A. Karsdal ; Chapter 34. The roles of collagens in cancer / N. Willumsen, N.I. Nissen and M.A. Karsdal ; Chapter 35. Use of extracellular matrix biomarkers in clinical research / A.R. Bihlet, M.A. Karsdal, ... C.L. Bager ; Chapter 36. Common confounders when evaluating noninvasive protein biomarkers / N. Willumsen, M.A. Karsdal and A. Kerrn-Jespersen ; Chapter 37. Implementation of collagen biomarkers in the clinical setting / E. Erhardtsen, D.G.K. Rasmussen and M.A. Karsdal.