Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Titre(s) : G protein-coupled receptors in health and disease [Texte électronique] / edited by Ya-Xiong Tao
Publication : Amsterdam ; Boston : Elsevier/Academic Press, cop. 2009
Description matérielle : 1 ressource dématérialisée
Collection : Progress in molecular biology and translational science ; v. 88-89
Note(s) : Includes bibliographical references and index
"G protein-coupled receptors (GPCRs) transduce signals from a diverse array of endogenous
ligands, including ions, amino acids, nucleotides, lipids, peptides, and large glycoprotein
hormones. They are also responsible for our sensing of exogenous stimuli, including
photons and odorants. GPCRs regulate almost every aspect of our physiological functions.
It is estimated that 40% to 50% of currently used therapeutic drugs target GPCRs directly
or indirectly. Because the current drugs target only a small portion of the GPCRs,
opportunities for targeting the remaining GPCRs is enormous. This volume reviews the
latest developments in this rapidly advancing field."--Publisher's website
Autre(s) auteur(s) : Tao, Ya-Xiong. Fonction indéterminée
Sujet(s) : Transduction du signal cellulaire
Protéines G -- Récepteurs
Protéines G -- Aspect sanitaire
Indice(s) Dewey :
612.015 (23e éd.) = Biochimie (physiologie humaine)
Identifiants, prix et caractéristiques : ISBN 9780123747563 . - ISBN 9780123747570
Identifiant de la notice : ark:/12148/cb447250345
Notice n° :
FRBNF44725034
(notice reprise d'un réservoir extérieur)
Table des matières : Part A: Rhodopsin-Mediated Retinitis Pigmentosa / Katherine M. Malanson and Janis
Lem ; Human Diseases Associated with GPR54 Mutations / Milena Gurgel Teles, Leticia
Ferreira Gontijo Silveira, Suzy Bianco and Ana Claudia Latronico ; Diseases Associated
with Growth Hormone-releasing hormone Receptor (GHRHR) Mutations / Marco Martari and
Roberto Salvatori ; The Melanocortin-1 Receptor Gene Polymorphism and Association
with Human Skin Cancer / Kimberley A. Beaumont, Yan Yan Liu and Richard A. Sturm ;
The Molecular Basis of Adrenocorticotrophin Resistance Syndrome / Lucila L K Elias
and Adrian J L Clark ; Mutations in melanocortin-4 receptor and human obesity / Ya-Xiong
Tao. ; Part B: Diseased G protein-coupled receptors: An Introduction / Ya-Xiong Tao
; GPR56 and its related diseases / Xianhua Piao and Ze Tian ; GnRHR mutations and
hypogonadotropic hypogonadism / Nicholas de Roux ; LHR mutations and reproductive
disorders / Deborah L. Segaloff ; FSHR mutations and reproductive disorde
