Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Titre(s) : Translation and its regulation in cancer biology and medicine [Texte électronique] / Armen Parsyan, editor
Publication : Dordrecht : Springer, [2014]
Description matérielle : 1 ressource dématérialisée
Note(s) : Includes bibliographical references and index
This book, for the first time, comprehensively assembles and analyzes a large body
of information on the role of the fundamental mechanism of the protein biosynthesis
pathway, translation, in cancer biology. It systematically explores the function of
the translation machinery and its regulation, including cell signaling, in the development,
maintenance and progression of human cancer. The work presented here unveils the tremendous
potential and applications of this vast and exciting branch of genetic, biochemical
and molecular science in cancer medicine and drug development. Chapters contributed
by experts in the field take the reader on a journey that starts with a dissection
of the translation machinery and its regulation in norm and cancer. Later chapters
characterize etiological and pathogenetic roles that translation plays in specific
cancer types. Various aspects of diagnostic, prognostic and therapeutic significance
of the translation machinery and its control in cancer are discussed. Readers will
discover the importance of the process of translation and its regulatory mechanisms
in physiology and cancer biology. The chapters and the numerous illustrations included
here were contributed by expert scientists and clinicians from renowned academic and
clinical establishments in Canada, the United States of America, the United Kingdom,
Italy, France, Belgium, Spain, Germany and Australia. The book conveys information
and knowledge that may interest a broad range of students and scholars ranging from
basic scientists to clinicians and drug developers seeking to better understand the
protein synthesis and its aberrations in cancer biology and cancer medicine
Autre(s) auteur(s) : Parsyan, Armen. Fonction indéterminée
Sujet(s) : Cancer -- Génétique
Cancer -- Étiologie
Traduction génétique
Cancer -- Aspect moléculaire
Cellules -- Prolifération
Indice(s) Dewey :
617 (23e éd.) = Chirurgie, médecine par régions du corps, dentisterie, ophtalmologie, otologie,
audiologie
Identifiants, prix et caractéristiques : ISBN 9789401790789
Identifiant de la notice : ark:/12148/cb44722906p
Notice n° :
FRBNF44722906
(notice reprise d'un réservoir extérieur)