Type(s) de contenu et mode(s) de consultation : Texte noté : électronique

Titre(s) : Coxiella burnetii [Texte électronique] : recent advances and new perspectives in research of the Q fever bacterium / Rudolf Toman ... [et al.], editors

Publication : Dordrecht ; New York ; London : Springer, c2012

Description matérielle : 1 ressource dématérialisée

Collection : Advances in experimental medicine and biology ; 984

Note(s) : Includes bibliographical references and index
Annotation ; Coxiella burnetii is the etiological agent of Q fever, a zoonotic disease found worldwide. The bacterium is a fascinating example of intracellular parasitism that has uniquely evolved to thrive in the most inhospitable of cellular compartments-the phagolysosome. Understanding how C. burnetii resists the degradative functions of this vacuole, and the host cell functions coopted for successful parasitism, are central to understanding Q fever pathogenesis. Recent achievements in glycomics and proteomics are guiding development of enhanced detection schemes for the bacterium in addition to shedding light on the host immune response to the pathogen. Several chapters survey immune functions that control or potentially exacerbate Coxiella infection and delve into correlates of protective immunity elicited by vaccination. Comparative genomics is also the foundation of chapters discussing diagnostic antigen discovery and molecular typing of the bacterium, with significance for development of new clinical, epidemiologic, and forensic tools

Autre(s) auteur(s) : Toman, Rudolf (Virologist). Fonction indéterminée  Voir les notices liées en tant qu'auteur

Sujet(s) : Coxiella burnetii  Voir les notices liées en tant que sujet
Fièvre Q -- Étiologie  Voir les notices liées en tant que sujet
Bactériologie médicale  Voir les notices liées en tant que sujet

Identifiants, prix et caractéristiques : ISBN 9789400743151

Identifiant de la notice  : ark:/12148/cb44721592r

Notice n° :  FRBNF44721592 (notice reprise d'un réservoir extérieur)

Table des matières : History and prospects of Coxiella burnetii research /Karim E. Hechemy ; Phylogenetic diversity, virulence and comparative genomics /Erin J. van Schaik and James E. Samuel ; Defense mechanisms against oxidative stress in Coxiella burnetii : adaptation to a unique intracellular niche /Katja Mertens and James E. Samuel ; Lipopolysaccharide of Coxiella burnetii /Craig T. Narasaki and Rudolf Toman ; Components of protective immunity /Guoquan Zhang, Yan Zhang, and James E. Samuel ; Proteome of Coxiella burnetii /Robert Ihnatko, Edward Shaw, and Rudolf Toman ; Coxiella subversion of intracellular host signaling /S. Kauser Hussain and Daniel E. Voth ; The Coxiella burnetii parasitophorous vacuole /Eric Ghigo, María I. Colombo, and Robert A. Heinzen ; Coxiella burnetii secretion systems /Justin A. McDonough, Hayley J. Newton, and Craig R. Roy ; Role of lipids in Coxiella burnetii infection /Stacey D. Gilk ; Axenic growth of Coxiella burnetii /Anders Omsland ; Developmental biology of Coxiella bur