Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Titre(s) : Lymphocyte trafficking in health and disease [Texte électronique] / Raffaele Badolato, Silvano Sozzani, editors
Titre d'ensemble : Springer e-books
Publication : Basel ; Boston : Birkhauser, 2006
Description matérielle : 1 online resource (x, 247 pages)
Collection : Progress in inflammation research
Note(s) : Includes bibliographical references and index
Since the discovery of chemokines and of chemokine receptors it has become evident
that expression of chemokines at the site of inflammation may regulate the composition
of cellular infiltrate, thereby directing the type of immune response. Recently, the
molecular characterization of inherited disorders of immune system, (e.g., Wiskott-Aldrich
syndrome, WHIM syndrome, leukocyte adhesion deficiency), which are characterized by
cytoskeleton/adhesion defects or by altered response of chemokine receptors has contributed
to clarifying the key players of immune response in normal physiology and in disease.
This book, which deals with the description of the role of chemokines in immune response
and underlines potential targets of therapeutical intervention, offers a series of
contributions of the most challenging aspects of lymphocyte migration in homeostasis
and in disease
Autre(s) auteur(s) : Badolato, Raffaele (1965-....). Fonction indéterminée
Sozzani, Silvano. Fonction indéterminée
Sujet(s) : Lymphocytes
Transport biologique
Médecine interne
Lymphocytes -- Métabolisme
Sciences de la vie
Indice(s) Dewey :
616.079 (23e éd.) = Immunité (médecine)
Identifiants, prix et caractéristiques : ISBN 9783764374426
Identifiant de la notice : ark:/12148/cb44714680j
Notice n° :
FRBNF44714680
(notice reprise d'un réservoir extérieur)
Table des matières : Lymphocyte trafficking: from immunology paradigms to disease mechanisms ; Lymphocyte
trafficking: from immunology paradigms to disease mechanisms ; Physiology of lymphocyte
trafficking ; Biology of chemokines ; Lymphocyte-endothelial cell interaction ;
Chemokine receptor expression in effector and memory T cell subsets ; Migration of
dendritic cell subsets ; Migration of NK cells ; Immunopathology of lymphocyte trafficking
; Lymphocyte trafficking and chemokine receptors during pulmonary disease ; Lymphocyte
migration to the brain ; Lymphocyte migration to the kidney ; Leukocyte migration
to pancreatic islets: a critical step in the pathogenesis of type 1 diabetes ; Controlling
leukocyte trafficking in disease ; Inherited disorders of lymphocyte trafficking
; Leukocyte adhesion deficiency ; Wiskott-Aldrich syndrome as a model of cytoskeleton
defects ; From CXCR4 mutations to WHIM syndrome.