Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Auteur(s) : Bhat, Paike Jayadeva
Titre(s) : Galactose regulon of yeast [Texte électronique] : from genetics to systems biology / Paike Jayadeva Bhat
Publication : Berlin : Springer, cop. 2008
Description matérielle : 1 online resource (xiv, 219 pages)
Note(s) : Includes bibliographical references and index
The galactose regulon of yeast is one of the best studied regulons. It is an ideal
paradigm for demonstrating fundamental and evolving concepts in biology and is used
in this book as a model system to explain various facets of conventional and modern
biology. The book starts with a brief historical overview on yeast research, i.e.
early observations in enzyme adaptation, classical genetics, formulating hypotheses
based on genetic inference. This is followed by molecular genetics of the galactose
regulon, isolation of genes and testing of the hypotheses. The power of mutational
analysis in deci
Sujet(s) : Galactose -- Génétique
Microorganismes -- Biotechnologie
Sciences de la vie
Identifiants, prix et caractéristiques : ISBN 9783540740155
Identifiant de la notice : ark:/12148/cb44695549v
Notice n° :
FRBNF44695549
(notice reprise d'un réservoir extérieur)
Table des matières : Introduction. An overview. Yeast is a eukaryotic model organism. A cell as a biochemical
entity ; Adaptation to Environment. Growth and multiplication. Enzyme adaptation.
Induction to Leloir enzymes ; Genetic Dissection of Galactose Metabolism. Genetic
analysis of GAL regulon. Genetic mapping of GAL genes ; Genetic Analysis GAL Genetic
Switch. Negative control by the repressor. Operator repressor model of GAL regulon.
Genetic interactions. Conditional lethal mutations. Revised model of GAL genetic switch.
Signal transduction in GAL regulon ; Molecular Genetics of GAL Regulon. Cloning:
a perspective. Genomic organization of GAL cluster. Isolation of GAL4: the transcriptional
activator. Isolation of GAL80: the repressor. Isolation of GAL3: the signal transducer
; Signal Transduction Revisited. Revised model of signal transduction. Genetic dissection
of signal transduction ; Versatile Galactose Genetic Switch. Transcription activation.
Glucose repression. Fine regulation of GAL g
