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010 .. $a 9783319350981
035 .. $a OCoLC946461391
100 .. $a 20170801d2016 m y0engy50 ba
101 0. $a eng
102 .. $a CH
105 .. $a a z 00|y|
106 .. $a s $a z
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181 .0 $6 01 $a i $b xxxe $a b $b xb2e
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200 1. $a Advances in respiratory cancerogenesis $b Texte électronique $f Mieczyslaw Pokorski, editor
210 .. $a [Cham] Switzerland $c Springer $d cop. 2016
215 .. $a 1 ressource dématérialisée
225 1. $a Advances in experimental medicine and biology $v volume 911 $i Neuroscience and respiration
300 .. $a Includes bibliographical references and index
330 .. $a "Lung cancer is the leading cause of mortality worldwide, with a low survival rate. Carcinogenesis generally requires a constellation of entwined steps, involving both innate cellular and environmental factors. This book shares the updated knowledge on the origin and development of cancer through genotypic changes which upset the physiological balance between cell proliferation, differentiation, growth control, and apoptosis. The emphasis is put on the role of microRNA proteins involved in the cellular processes above outlined. Cognitive changes, related to dysregulated cellular mechanisms in cancer cells, as yet unchartered area of research, also are tackled. A better understanding of the molecular and cellular biology of lung cancer is the key source of breakthroughs in the diagnosis and prognosis, and finding more effective therapies that target specific mutations. The book provides a source of current facts and trends in clinical research and practice. It will be of interest to clinicians, researchers, and other medical professionals"--Back cover
606 .. $3 11934908 $a Appareil respiratoire $3 11931105 $x Cancer $2 rameau
676 .. $a 616.994 2 $v 23
702 .| $3 17268059 $a Pokorski $b Mieczyslaw $4 570
801 .3 $a US $b OCoLC $c 20170801 $h 946461391 $2 marc21
801 .0 $b NLM $g rda
930 .. $5 FR-759999999:44681143001001 $a ACQNUM-62909 $b 759999999 $c Document numérisé $d N

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