Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Auteur(s) : Stein, Ross L.
Titre(s) : Kinetics of enzyme action [Texte électronique] : essential principles for drug hunters / Ross L. Stein
Publication : Hoboken, N.J. : John Wiley, cop. 2011
Description matérielle : 1 ressource dématérialisée
Note(s) : Includes bibliographical references and index
"Few scientists have the knowledge to perform the studies that are necessary to discover
and characterize enzyme inhibitors, despite the vested interest the pharmaceutical
industry has in this field. Beginning with the most basic principles pertaining to
simple, one-substrate enzyme reactions and their inhibitors, and progressing to a
thorough treatment of two-substrate enzymes, Kinetics of Enzyme Action: Essential
Principles for Drug Hunters provides biochemists, medicinal chemists, and pharmaceutical
scientists with numerous case study examples to outline the tools and techniques necessary
to perform, understand, and interpret detailed kinetic studies for drug discovery"--Provided
by publisher
Sujet(s) : Enzymes -- Pharmacocinétique
Antienzymes -- Pharmacocinétique
Indice(s) Dewey :
572.7 (23e éd.) = Enzymes
Identifiants, prix et caractéristiques : ISBN 9781118084410
Identifiant de la notice : ark:/12148/cb44652529p
Notice n° :
FRBNF44652529
(notice reprise d'un réservoir extérieur)
Table des matières : Kinetics of single-substrate enzymatic reactions ; Kinetics of single-substrate enzymatic
reactions : special topics ; Enzyme inhibition : the phenomenon and mechanistic analysis
; Kinetic mechanism of inhibition of one-substrate enzymatic reactions ; Tight-binding,
slow-binding, and irreversible inhibitors ; Kinetics of two-substrate enzymatic reactions
; Kinetic mechanism of inhibition of two-substrate enzymatic reactions ; Allosteric
modulation of enzyme-catalyzed reactions ; Kinetics-based probes of enzyme mechanisms.
