Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Auteur(s) : Wu, Rongling
Titre(s) : Statistical genetics of quantitative traits [Texte électronique] : linkage, maps, and QTL / Rongling Wu, Chang-Xing Ma, George Casella
Publication : New York : Springer, cop. 2007
Description matérielle : 1 ressource dématérialisée
Collection : Statistics for biology and health
Note(s) : Includes bibliographical references (pages 343-354) and indexes
The book introduces the basic concepts and methods that are useful in the statistical
analysis and modeling of DNA-based marker and phenotypic data that arise in agriculture,
forrestry, experimental biology, and other fields. It concentrates on the linkage
analysis of markers, map construction and quantitative trait locus (QTL) mapping and
assumes a background in regression analysis and maximum likelihood approaches. The
strengths of this book lie in the construction of general models and algorithms for
linkage analysis and QTL mapping in any kind of crossed pedigrees initiated with inbred
lines of crops and plant and animal model systems or outbred lines in forest trees
and wildlife species. The book includes a detailed description of each approach and
the step-by-step demonstration of live-example analyses designed to explain the utilization
and usefulness of statistical methods. It also includes exercise sets and computer
codes for all the analyses used. It can serve as a
Autre(s) auteur(s) : Ma, Chang-Xing. Fonction indéterminée
Casella, George (1951-....). Fonction indéterminée
Sujet(s) : Génétique -- Méthodes statistiques
Chromosomes -- Cartes
Liaison génétique
Indice(s) Dewey : 576.53 (23e éd.) = Matériel génétique ; 576.501 5195 (23e éd.) = Génétique - Principes statistiques
Identifiants, prix et caractéristiques : ISBN 9780387681542
Identifiant de la notice : ark:/12148/cb44642993p
Notice n° :
FRBNF44642993
(notice reprise d'un réservoir extérieur)
Table des matières : Basic genetics ; Basic statistics ; Linkage analysis and map construction ; A general model for linkage analysis in controlled crosses ; Linkage analysis with recombinant inbred lines ; Linkage analysis for distorted and misclassified markers ; Special considerations in linkage analysis ; Marker analysis of phenotypes ; The structure of QTL mapping ; Interval mapping with regression analysis ; Interval mapping by maximum likelihood approach ; Threshold and precision analysis ; Composite QTL mapping ; QTL mapping in outbred pedigrees.