Type(s) de contenu et mode(s) de consultation : Texte : électronique

Titre(s) : Peptide nucleic acids, morpholinos and related antisense biomolecules [Texte électronique] / [edited by] Christopher G. Janson, Matthew J. During

Publication : Georgetown, Tex. : Landes Bioscience/Eurekah.com ; New York, N.Y. : Kluwer Academic/Plenum Publishers, cop. 2006

Description matérielle : 1 online resource (274 pages)

Collection : (Medical intelligence unit)

Note(s) : Includes bibliographical references and index
This volume is unique to the existing literature in the Peptide Nucleic Acid field, in that it focuses on comparing and contrasting PNA with other available oligonucleotide homologues and considers areas in which these biomolecules could be profitably applied to clinical and diagnostic applications. Part I of the book addresses comparative strengths and weaknesses of various nucleoside homologues. Part II of the book addresses specific translational or clinical applications for PNA and related antisense biomolecules. The editors have succeeded in presenting a balanced yet broad view of the methods available for gene targeting and modification

Autre(s) auteur(s) : Janson, Christopher G.. Fonction indéterminée  Voir les notices liées en tant qu'auteur
During, Matthew J.. Fonction indéterminée  Voir les notices liées en tant qu'auteur

Sujet(s) : Acides nucléiques antisens  Voir les notices liées en tant que sujet
Peptides antisens  Voir les notices liées en tant que sujet
Sciences de la vie  Voir les notices liées en tant que sujet

Indice(s) Dewey : 612.015 756 (23e éd.)  Voir les notices liées en tant que sujet

Numéros : ISBN 9780387329567

Notice n° :  FRBNF44642287 (notice reprise d'un réservoir extérieur)

Table des matières : The many faces of PNA / Peter E. Nielsen ; Modulation of nucleic acid information processing by PNAs : potential use in anti-viral therapeutics / Lionel Bastide, Bernard Lebleu and Ian Robbins ; Targeted gene delivery : the role of peptide nucleic acid / Kenneth W. Liang, Feng Liu and Leaf Huang ; Imaging gene expression in the brain with peptide nucleic acid (PNA) antisense radiopharmaceuticals and drug targeting technology / Ruben J. Boado and William M. Pardridge.
Receptor-specific targeting with complementary peptide nucleic acids conjugated to peptide analogs and radionuclides / Eric Wickstrom, Mathew L. Thakur and Edward R. Sauter ; Morpholinos and PNAs compared / James E. Summerton ; Chemistry of locked nucleic acids (LNA) : design, synthesis and bio-physical properties / Jesper Wengel [and others] ; Recent applications of RNA interference (RNAi) in mammalian systems / Lisa Scherer and John J. Rossi ; Peptide nucleic acids as epigenetic inhibitors of HIV-1 / Shizuko Sei ; Therapeutic uses of peptide nucleic acids (PNA) in oncology / Nadia Zaffaroni, Raffaella Villa and Marco Folini.
PNAs as novel cancer therapeutics / Luca Mologni and Carlo Gambacorti-Passerini ; Medicinal chemistry of plasmid DNA with peptide nucleic acids : a new strategy for gene therapy / Olivier Zelphati [and others] ; Locked nucleic acids (LNA) and medical applications / Henrik Ørum, Andreas Wolter and Lars Kongsbak ; Peptide nucleic acids as agents to modify target gene expression and function / Gan Wang and Peter M. Glazer ; Peptide nucleic acids : cellular delivery and recognition of DNA and RNA targets / David R. Corey.
The use of PNAs and their derivatives in mitochondrial gene therapy / Paul M. Smith [and others] ; Gene silencing through RNA interference: potential for therapeutics and functional genomics / David O. Azorsa, Spyro Mousses and Natasha J. Caplen ; Transcriptional activation of human CREB gene promoter using bis-PNA (peptide nucleic acid) / Christopher G. Janson [and others].