Notice bibliographique

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181 .0 $6 01 $a i $b xxxe
181 .. $6 02 $c txt $2 rdacontent
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182 .. $6 02 $c c $2 rdamedia
200 1. $a Modeling in biopharmaceutics, pharmacokinetics, and pharmacodynamics $b Texte électronique $e homogeneous and heterogeneous approaches $f Panos Macheras, Athanassios Iliadis
210 .. $a New York, NY $c Springer New York $c Springer e-books $d 2006
215 .. $a 1 online resource
225 1. $a Mathematics and Statistics (Springer-11649; ZDB-2-SMA)
225 1. $a Interdisciplinary applied mathematics $v 30
225 1. $a Mathematics and Statistics (Springer-11649)
300 .. $a Titre provenant de la page de titre du document numérisé
300 .. $a Numérisation de l'édition de New York : Springer, 2006
300 .. $a Bibliogr. p. 383-432. Index
330 .. $a The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. This timely and useful book will appeal to graduate students and researchers in pharmacology, pharmaceutical sciences, bioengineering, and physiology
336 .. $a Fichiers PDF.
336 .. $a Fichier PDF.
606 .. $3 11946864 $a Biopharmacie $3 11956771 $x Modèles mathématiques $2 rameau
606 .. $3 11933093 $a Pharmacocinétique $3 11956771 $x Modèles mathématiques $2 rameau
606 .. $3 11932467 $a Pharmacodynamie $3 11956771 $x Modèles mathématiques $2 rameau
676 .. $a 570.151 $v 23
700 .| $3 17250097 $a Macheras $b Panos $4 070
701 .| $3 17232767 $a Iliadis $b Athanassios $f 1950-.... $4 070
701 .| $3 17232766 $a Iliadis $b Athanassios $4 070
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930 .. $5 FR-759999999:44642224001001 $a ACQNUM-23990 $b 759999999 $c Document numérisé $d N

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