Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Auteur(s) : Gomperts, B. D.
Titre(s) : Signal transduction [Texte électronique] / Bastien D. Gomperts, University of Bordeaux, European Institute of Chemistry and Biology, INSERM U1045, Talence, France
Édition : 3d edition
Publication : Amsterdam ; Boston : Elsevier/AP, [2016]
Description matérielle : 1 ressource dématérialisée
Note(s) : Includes bibliographical references and index
"A reference on cellular signaling processes, the third edition of Signal Transduction
continues in the tradition of previous editions, in providing a historical overview
of how the concept of stimulus-response coupling arose in the early twentieth century
and shaped our current understanding of the action of hormones, cytokines, neurotransmitters,
growth factors and adhesion molecules. In a new chapter, an introduction to signal
transduction, the book provides a concise overview of receptor mechanisms, from receptor
-ligand interactions to post-translational modifications operational in the process
of bringing about cellular changes. The phosphorylation process, from bacteria to
men, is discussed in detail. Signal transduction third edition further elaborates
on diverse signaling cascades within particular contexts such as muscle contraction,
innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic
transformation and cell fate decision during development or in stem cell niches. The
subjects have been enriched with descriptions of the relevant anatomical, histological,
physiological or pathological condition."--Page 4 of cover
Sujet(s) : Transduction du signal cellulaire
Indice(s) Dewey :
571.74 (23e éd.) = Biochimie de la régulation
Identifiants, prix et caractéristiques : ISBN 9780123948038
Identifiant de la notice : ark:/12148/cb44635203g
Notice n° :
FRBNF44635203
(notice reprise d'un réservoir extérieur)
Table des matières : Prologue : signal transduction from an historical perspective ; An introduction to
signal transduction ; Regulation of muscle contraction by adrenoceptors ; Cholinergic
signaling and muscle contraction ; Sensory signal processing : visual transduction
and olfaction ; Intracellular calcium ; Bringing the signal into the nucleus : regulation
of gene expression ; Nuclear receptors ; Protein kinase C in oncogenic transformation
and cell polarity ; Regulation of cell proliferation by receptor tyrosine protein
kinases ; Signal transduction to and from adhesion molecules ; WNT signaling and
the regulation of cell adhesion and differentiation ; Activation of the innate immune
system : the toll-like receptor-4 and signaling through ubiquitinylation ; Chemokines
and traffic of white blood cells ; Activating the adaptive immune system : role of
non-receptor tyrosine kinases ; Signaling through the insulin receptor : phosphoinositide
3-kinases and AKT ; TGFß and signaling throug
