Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Titre(s) : Polypharmacology in drug discovery [Texte électronique] / edited by Jens-Uwe Peters
Publication : Hoboken, N.J. : Wiley, cop. 2012
Description matérielle : 1 online resource (1 texte électronique)
Note(s) : In Wiley online library. - Titre de l'écran-titre (visionné le 31 juillet 2012). - Bibliogr
"Covers the two-sided nature of polypharmacology--its contribution to adverse drug
reactions and its benefit in certain therapeutic drug classes. Addresses the important
topic of polypharmacology in drug discovery, a subject that has not been thoroughly
covered outside of scattered journal articles Overviews state-of-the-art approaches
and developments to help readers understand concepts and issues related to polypharmacology"--Résumé
de l'éditeur
Autre(s) auteur(s) : Peters, Jens-Uwe. Fonction indéterminée
Sujet(s) : Pharmacologie
Indice(s) Dewey :
615.19 (23e éd.) = Chimie pharmaceutique
Identifiants, prix et caractéristiques : ISBN 9781118098141
Identifiant de la notice : ark:/12148/cb44652580f
Notice n° :
FRBNF44652580
(notice reprise d'un réservoir extérieur)
Table des matières : Frontmatter ; Color Plates ; Introduction: The Case for Polypharmacology / Andrew
L Hopkins ; Polypharmacology: A Safety Concern in Drug Discovery. The Relevance of
Off-Target Polypharmacology / Bruce D Car ; Screening for Safety-Relevant Off-Target
Activities / Laszlo Urban, Steven Whitebread, Jacques Hamon, Dmitri Mikhailov, Kamal
Azzaoui ; Pharmacological Promiscuity and Molecular Properties / Jens-Uwe Peters
; Kinases as Antitargets in Genotoxicity / Stephan Kirchner ; Activity at Cardiovascular
Ion Channels: A Key Issue for Drug Discovery / Ian M Bell, Mark T Bilodeau, Armando
A Lagrutta ; Prediction of Side Effects Based on Fingerprint Profiling and Data Mining
/ Jacques Migeon ; Polypharmacology: An Opportunity for Drug Discovery. Polypharmacological
Drugs: ₃Magic Shotguns₄ for Psychiatric Diseases / Wesley K Kroeze, Bryan L Roth ;
Polypharmacological Kinase Inhibitors: New Hopes for Cancer Therapy / Annalisa Petrelli
; Polypharmacology as an Emerging Trend
