Notice bibliographique
- Notice
Type(s) de contenu et mode(s) de consultation : Texte noté : électronique
Titre(s) : Spider venoms [Texte électronique] / P. Gopalakrishnakone, editor-in-chief ; Gerardo Corzo, Maria Elena de Lima, Elia Diego-García, editors
Publication : Dordrecht : Springer Reference, 2015
Description matérielle : 1 online resource (550 pages)
Collection : Toxinology
Note(s) : Handbook.. - Includes index.
This volume provides an overview of the biochemical characterization, structure-function
studies, proteomics, bioinformatics, molecular biology, transcriptomics and genomics
of various spider species. The book also covers our current knowledge of venom components,
toxins and their modes of action. The first section of Spider Venom includes contributions
regarding the wide diversity of spider venom components and depicts some of their
biological effects (antimicrobial, ion channel modulators, insecticides, this includes
peptide and non-peptide toxins), and emphasizes spiders of public health importance.
The second section covers transcriptomes, proteomes (and peptidomics), bioinformatics
and molecular dynamics. The last section describes antimicrobial, insecticidal toxins,
envenomation and the medical potential of spider venoms. Spider venoms are a great
and extensive source of bioactive compounds, and as such form a boundless and bountiful
area awaiting discovery. It is by virtue of dedicated scientists that new toxins are
discovered and that new insights arise, leading the way towards the investigation
of their pharmacological effects, and hopefully, as a consequence, arriving at the
discovery of venom components as new drug candidates.
Autre(s) auteur(s) : Gopalakrishnakone, P.. Auteur ou responsable intellectuel
Corzo, Gerardo. Auteur ou responsable intellectuel
Lima, Maria Elena de (1953-....). Auteur ou responsable intellectuel
Diego-García, Elia. Auteur ou responsable intellectuel
Indice(s) Dewey :
615.19 (23e éd.) = Chimie pharmaceutique
Identifiants, prix et caractéristiques : ISBN 9789400763890
Identifiant de la notice : ark:/12148/cb45126840n
Notice n° :
FRBNF45126840
(notice reprise d'un réservoir extérieur)
Table des matières : Anticancer Potential of Spider Venom -- Antimicrobial Peptides in Spider Venoms. -
Antimicrobial, Insecticides, Analgesics, and Hyalurodinases from the Venom Glands
of Brachypelma Spiders -- Bioecology of Spiders with Emphasis in Spiders of Public
Health Importance -- Hippasa Spider, Biology, Envenomation, Toxin Profiles, Biological
Functions: A Review. - Identifying Insect Protein Receptors Using an Insecticidal
Spider Toxin -- In Silico Modeling of Spider Toxins: Bioinformatics, Molecular Docking,
and Molecular Dynamics -- Loxosceles and Loxoscelism: Biology, Venom, Envenomation
and Treatment -- Pain-Modulating Peptides in Spider Venoms: Good and Evil -- Peptidom
and Transcriptom Analysis of the Toxin-Like Peptides in the Venom Glands of Tarantula
Grammostola Rosea. - Phoneutria nigriventer Venom and Toxins: A Review -- Phoneutria
nigriventer Venom: Action in the Central Nervous System. - Recent Insights in Latrodectus
("Black Widow" Spider) Envenomation: Toxins and Their Mechanisms of Action -- Spider
Transcriptomes from Venom Glands: Molecular Diversity of Ion Channel Toxins and Antimicrobial
Peptide Transcripts -- Spider Venom and Drug Discovery: A Review. - Structural Diversity
and Basic/Acidic Residue Balance of Active Cysteine-Rich Insecticidal Peptides from
Spiders -- Studying the Excitatory and Inhibitory Neurotransmissions with Spider Venoms.
- The Non-peptide Low Molecular Mass Toxins from Spider Venoms -- The Venom from Lasiodora
sp.: A Mygalomorph Brazilian Spider -- The Venom of Australian Spiders -- Venom of
Cupiennius salei (Ctenidae).